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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Pantothenic Acid
drug:
Probenecid
Research Papers that Mention the Interaction
“…,probenecid and ouabain (both 1 mM) and …, nonanoate, and decanoate) profoundly inhibited [3H]pantothenic acid accumulation by forebrain slices but not intracellular phosphorylation and conversion to [3H]CoA. These in vitro results … saturable system (probably facilitated diffusion) that is sensitive to inhibition by probenecid and medium‐chain fatty acids.”
Development and Characterization of Pantothenic Acid Transport in Brain“ PA (0.3 μM) transport through the blood‐brain barrier was significantly inhibited by probenecid , nonanoic acid, and biotin (all 0.25 mM), but not by penicillin G, pyruvate, β‐hydroxybutyrate.”
“ Probenecid can inhibit effectively the renal tubular secretion of pantothenic acid in man.”
Renal Clearance of Pantothenic Acid in Man
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