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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Pancreatic Lipase
supplement:
Saponin
Research Papers that Mention the Interaction
“DESIGN: For in vitro experiments, assay for the inhibitory effects of teasaponin on pancreatic lipase activity was performed by measuring the rate of release of oleic acid from triolein in an assay system using triolein emulsified with lecithin, gum arabic, Triton X-100 or 4-methylumbelliferyloleate.”
“OBJECTIVE: Based on the inhibitory effects of teasaponin on pancreatic lipase activity in vitro, this study was performed to clarify whether teasaponin prevented obesity induced in mice by a high-fat diet for 11 weeks.”
Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor“On the other hand, the total saponin fraction of the aqueous extract inhibited pancreatic lipase activity in vitro.”
“By using a pancreatic lipase-inhibiting assay system, the crude saponin fraction showed inhibitory activity on pancreatic lipase , which is a key enzyme in lipid digestion.”
Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus.
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