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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Palmitic Acid
supplement:
Palmitoleic Acid
Research Papers that Mention the Interaction
“We report a significant association between palmitic acid (16:0), palmitoleic acid (16:1n-7) concentrations and ratio of monounsaturated to saturated fatty acid ( palmitoleic acid to palmitic acid) and higher liver fat content.”
Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes.“… palmitoleic and oleic acid at a concentration of 0.2 … completely inhibit the proapoptotic effect of their counterpart saturated palmitic and stearic acid at a concentration of 1 mM. Apoptosis induced by stearic acid was …-6, -7, -9, -2 and -8, but not with significant activation of caspase-3.”
“Finally, palmitoleic acid improved beta-cell-secretory function that was reduced by palmitic acid.”
“In contrast, the monounsaturated palmitoleic acid does not affect beta-cell apoptosis, yet it promotes beta-cell proliferation at low glucose concentrations, counteracting the negative effects of palmitic acid as well as improving beta-cell function.”
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function.“Increased levels of palmitoleic acid resulted from an increased desaturation of palmitic acid.”
“Similarly palmitic and stearic acids are competitive inhibitors of palmitoleic acid activation (Ki = 2.4 and 17.3 µm, respectively).”
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