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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Palmitic Acid
supplement:
Docosahexaenoic Acid
Research Papers that Mention the Interaction
“These results show that the positional specificity of human LCAT is altered when the concentration of 16:0 -22:6 PC is increased by DHA supplementation.”
Evidence for altered positional specificity of LCAT in vivo: studies with docosahexaenoic acid feeding in humans.“Results also showed that DHA inhibited the cooperative effect of LPS and PA on CER production by targeting CER de novo synthesis, but not SM hydrolysis.”
“Results showed that DHA strongly inhibited the synergistic effect of LPS and PA on proinflammatory gene expression by targeting nuclear factor kappa B (NFκB)-dependent gene transcription.”
“Taken together, this study demonstrates that DHA antagonizes the boosting effect of PA on LPS signaling on proinflammatory gene expression by targeting both NFκB-dependent transcription and CER de novo synthesis in macrophages.”
Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis
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