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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Paclitaxel
supplement:
Phosphatidylserine
Research Papers that Mention the Interaction
“The PS-containing formulations were found to be pro-apoptotic and exhibited strong synergism between PS and paclitaxel (Combination Index, CI < 0.1).”
Pro-apoptotic liposomes-nanobubble conjugate synergistic with paclitaxel: a platform for ultrasound responsive image-guided drug delivery“The formulation, with synergistic inputs from PS and paclitaxel , downregulated Ki-67 and inhibited angiogenesis leading to apoptosis by activating caspase-3 and downregulating Bcl-2, resulting in DNA fragmentation.”
“Imatinib alone or with paclitaxel significantly reduced PS by 35% (one‐tailed paired t‐test, P = 0.045) and 40% (P = 0.0003), respectively, whereas paclitaxel alone or no treatment had no effect.”
Macromolecular dynamic contrast‐enhanced (DCE)‐MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti–platelet‐derived growth factor receptor (PDGFR) therapy, indicating a drop in vascular endothelial growth factor receptor (VEGFR) activation
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