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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Paclitaxel
supplement:
Magnesium Isoglycyrrhizinate
Research Papers that Mention the Interaction
“In spite of the insignificance of decreased system exposure of paclitaxel and recovered hepatic function by MI , they did correlate with each other.”
“It was therefore deduced that the liver toxicities of paclitaxel plus cisplatin chemotherapy potentially decrease hepatic elimination and increase system exposure of paclitaxel, and the recovery of liver function by MI helps to restore hepatic clearance of paclitaxel.”
“It was … MRT of paclitaxel were significantly (…) reduced by MI , respectively, from 11.0 ± 2.2 and 5.6 ± 1.0 h to 7.7 ± 1.7 and 4.0 ± … indicated by platelet count and hepatic events marked with ALT, AST and γ-GT were significant in both groups.”
Increased elimination of paclitaxel by magnesium isoglycyrrhizinate in epithelial ovarian cancer patients treated with paclitaxel plus cisplatin: a pilot clinical study
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