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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Paclitaxel and Kanglaite

supplement:

Kanglaite

Research Papers that Mention the Interaction

Kanglaite inhibited the expression of nuclear factor (NF)-κΒ and upregulated that of connexin 43, both of which sensitized cancer cells to Taxol.
Kanglaite pretreatment followed by Taxol treatment was found to show the best synergism among all combination strategies.
Moreover, Kanglaite increased many cellular variations caused by Taxol , including tubulin polymerization, caspase-3 cleavage, and upregulated expression of survivin and cyclin B1.
These results suggest that Kanglaite pretreatment may increase the effect of Taxol on colorectal cancer.
Scientific Reports  •  2017  |  View Paper
Conclusion: Paclitaxel combined with kanglaite is more effective than paclitaxel or kanglaite alone in improving bone metastasis of lung cancer and has an important significance in clinical treatment of bone metastasis of lung cancer.
Iranian journal of public health  •  2019  |  View Paper