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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Paclitaxel and Intralipid

supplement:

Intralipid

Research Papers that Mention the Interaction

Here, we have found that Intralipid reduces the cytotoxicity of paclitaxel for human monocytic cells, but not for breast, lung, or pancreatic cancer cells.
Using a xenograft breast cancer mouse model, we have found that Intralipid pre-treatment significantly increases the amount of paclitaxel reaching the tumor and promotes tumor apoptosis.
Scientific Reports  •  2020  |  View Paper
Similarly, the droplet size of Intralipid increased from 283.3 to 294.6nm on inclusion of 6mg/ml paclitaxel.
International journal of pharmaceutics  •  2016  |  View Paper