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Last Updated: 3 years ago

Possible Interaction: Oxytocin and Tamoxifen

supplement:

Oxytocin

Research Papers that Mention the Interaction

In these same cells, OT administration significantly enhances the inhibitory effect of tamoxifen on cell proliferation.
Virchows Archiv  •  2004  |  View Paper
The increase in OT mRNA was antagonized by tamoxifen , suggesting that the effects were estrogen receptor mediated.
The Journal of clinical endocrinology and metabolism  •  1995  |  View Paper
OXT was stimulatory to E2 and P secretion, an effect that can be blocked by a specific OXT antagonist and by tamoxifen.
The Journal of clinical endocrinology and metabolism  •  1992  |  View Paper
TAM inhibited the increase in serum E2, uterine ER, and OT mRNA and peptide, but had no effect on serum P4 or uterine PR levels.
Endocrinology  •  1996  |  View Paper
The stimulation of P release by OXT could be antagonized by prior treatment of the CL with tamoxifen.
Endocrinology  •  1990  |  View Paper
The non-steroidal antioestrogen tamoxifen trans-1-(4-beta-dimethylaminoethoxyphenyl)-1,2-diphenylbut- 1-ene ), widely used in the treatment of breast cancer, and its oestrogenic cis-isomer rapidly inhibited contractile responses of isolated rat myometrium to supramaximal concentrations of oxytocin (1.28 X 10(-6) mol/l).
The Journal of endocrinology  •  1984  |  View Paper