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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Oxytocin
drug:
Substance P
Research Papers that Mention the Interaction
“Intracerebroventricular (icv) injection of substance P (SP) or highly selective NK-1 receptor agonist--[(Sar(9),Met(O2)(11))-Substance P]-- significantly stimulated the OT secretion from the rat neurohypophysis into the general circulation.”
Oxytocin release from the rat neurohypophysis into the blood: effects of tachykinin NK-1 and NK-2 receptors agonists and antagonists.“The present results show that the stimulatory effect of substance P on basal release of AVP and OT from rat hypothalamo-neurohypophysial system in vitro is sensitive to inhibitory influence of melatonin.”
“The present results show that substance P stimulates basal AVP and OT release from isolated hypothalamo-neurohypophysial system, when used at the concentrations of 10(-6) and 10(-7)M/l.”
“ SP elicited a concentration-dependent stimulation of VP and OT release that was large and sustained compared with other stimuli.”
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