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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Oxytocin
drug:
Propranolol
Research Papers that Mention the Interaction
“ Propranolol had no effect on progesterone secretion yet significantly (P < 0.05) reduced oxytocin concentrations on Day 3.”
Effect of adrenalin and propranolol on progesterone and oxytocin secretion in vivo during the caprine estrous cycle.“This increase was more rapid and greater after oxytocin than under control conditions or after apomorphine injection, and was delayed and reduced after propranolol.”
“In euhydrated rats the single dose of propranolol diminished significantly the vasopressin and oxytocin content in the neurohypophysis.”
“In not dehydrated animals the only dose of propranolol increased significantly the vasopressin and oxytocin release from the neurohypophysis.”
“ Propranolol (1.10(-6) g/ml) decreased the … hyperpolarization response of the MP to oxytocin by 36%; 1.10(-9)--1.10(-8) g/ml of isadrine induced a 42% and 53% …, and 1.10(-7)--1.10(-5) g/ml blocked the response of secretory cells to oxytocin.”
“ Propranolol and its optical isomers shifted the dose-response curve of oxytocin to the right.”
“Frequency of cesarean section deliveries significantly decreased in the propranolol plus oxytocin group compared to the placebo plus oxytocin group (P = 0.005, P = 0.015) on the first and the second days, respectively.”
The effect of oral propranolol plus oxytocin versus oxytocin only on the process and outcome of labor: A double-blind randomized trial
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