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Last Updated: 3 years ago

Possible Interaction: Oxytocin and Phosphatidylinositol 4,5-Diphosphate

supplement:

Oxytocin

supplement:

Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

“Manipulations of PIP2 levels affected both medium and slow AHP currents in oxytocin ( OT ) neurons of the supraoptic nucleus.”
“ PIP2 appears to influence AHPs in OT neurons by reducing Ca2+ influx during spiking.”
Phosphatidylinositol 4,5‐bisphosphate (PIP2) modulates afterhyperpolarizations in oxytocin neurons of the supraoptic nucleus
The Journal of physiology  •  2017  |  View Paper
“In the guinea pig myometrium, carbachol, oxytocin , and fluoroaluminates stimulated the breakdown of phosphatidylinositol 4,5-bisphosphate , which was insensitive to pertussis toxin [Biochem.”
Activation of beta-adrenergic receptors inhibits Ca2+ entry-mediated generation of inositol phosphates in the guinea pig myometrium, a cyclic AMP-independent event.
Molecular pharmacology  •  1992  |  View Paper