supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
supplement:
Oxytocin
drug:
Papaverine
Research Papers that Mention the Interaction
“The increase of oxygen consumption in the H-65K+ or oxytocin was significantly inhibited by papaverine (1-100 microM).”
Mechanism of relaxant response to papaverine on the smooth muscle of non-pregnant rat uterus.“ Papaverine produced a decrease in the frequency and amplitude of contractile responses induced by oxytocin , and these inhibitory effects were observed regardless of whether papaverine was added before or after the induced contractions.”
“The increase in 45Ca space by carbachol and oxytocin was inhibited by papaverine.”
“ Oxytocin produced an acute decrease in this threshold dose on phentolamine or methysergide, but was inhibited by papaverine , dibutyryl cAMP, salbutamol and verapamil.”
“Graded concentrations of salbutamol, isoproterenol, papaverine , theophylline, thioglycollate, and MgCl2 produced a decrease in the maximal effect of oxytocin and a shift of the concentration-effect curves to the right.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback