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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Oxytocin
drug:
Nimesulide
Research Papers that Mention the Interaction
“Conclusion: The results show that nimesulide lowers spontaneous myometrial contractility and sensitivity to oxytocin while increasing sensitivity to PGs, indicating a down-regulation of oxytocin receptor and an up-regulation of PG receptors and/or intracellular signaling events.”
In Vivo Administration of Nimesulide, a Selective PGHS-2 Inhibitor, Increases In Vitro Myometrial Sensitivity to Prostaglandins While Lowering Sensitivity to Oxytocin
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