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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Oxytocin
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“ magnesium ions were found to augment the response to the U.S.P. Standard, oxytocin , lysine and arginine vasopressins and all the analogues tested, but there was considerable variation between substances in the degree to which this potentiation occurred.”
Effect of magnesium ion on the response of the rat uterus to neurohypophysial hormones and analogues.“Also observed was the effect of magnesium concentrations on the ability of OT to induce changes in epididymal contractility.”
“Furthermore, we noted that Mg++ has an inverse correlation with the frequency of contractions of the caput epididymis both in the presence and absence of OT.”
The effects of oxytocin and arginine vasopressin in vitro on epididymal contractility in the rat.“ Oxytocin induced a Na+ and K+ increase, a Ca++ decrease, and slight changes in Mg++.”
“Since Mg++ increases the potency as well as the maximal response to oxytocin , it is probable that Mg++ may in some manner also increase the reactivity on reduce the threshold of excitation-contraction coupling in the contractile system sensitive to the neumohypophysial peptides.”
“The effect of Mg++ on the activity of oxytocin and PGs was both quantitatively and qualitatively different.”
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