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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Preincubation in PHM1-41 cells with chlorophenylthio-cAMP (CPT-cAMP), forskolin , or relaxin inhibited the ability of oxytocin to stimulate phosphatidylinositide turnover.”
Protein kinase A anchoring to the myometrial plasma membrane is required for cyclic adenosine 3',5'-monophosphate regulation of phosphatidylinositide turnover.“ Oxytocin and atosiban, but not retosiban inhibited forskolin and calcitonin stimulated cAMP production.”
“ Oxytocin enhanced the effects of forskolin on progesterone production.”
“In membrane discs, forskolin preincubation also inhibited oxytocin , PMA and EGF stimulation of PGE2 production.”
“Although ovarian steroids showed no effect on OT receptors, forskolin (an adenylate cyclase activator) and dibutyryl cAMP caused 1.5- to 1.6-fold increases in specific binding of OT without changing the binding affinity.”
Up-regulation of oxytocin receptors in porcine endometrium by adenosine 3',5'-monophosphate.“(Bu)2AMP, forskolin , or cholera toxin caused 2- to 8-fold increases in specific binding of iodinated OT antagonist.”
“Judging from the greater effects on PGE2 release, these results suggest that forskolin and cortisol up-regulate the signal response mechanism to OT as well as the OTR concentration.”
“Both forskolin and PMA (phorbol 12-myristate 13-acetate) increased CRF, AVP and oxytocin release, while dexamethasone and aldosterone only reduced basal secretion of CRF.”
“ Forskolin elicited a 3-fold greater increase in cyclic AMP in the neural lobe than in the supraoptic nucleus and enhanced the sensitivity of the tissues to both vasopressin and oxytocin.”
“(Bu)2cAMP and forskolin also inhibited the effect of oxytocin on intracellular calcium.”
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