Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Oxytocin and Colforsin

supplement:

Oxytocin

Research Papers that Mention the Interaction

Preincubation in PHM1-41 cells with chlorophenylthio-cAMP (CPT-cAMP), forskolin , or relaxin inhibited the ability of oxytocin to stimulate phosphatidylinositide turnover.
Endocrinology  •  1999  |  View Paper
Oxytocin and atosiban, but not retosiban inhibited forskolin and calcitonin stimulated cAMP production.
Endocrinology  •  2020  |  View Paper
Oxytocin enhanced the effects of forskolin on progesterone production.
Biology of reproduction  •  2002  |  View Paper
In membrane discs, forskolin preincubation also inhibited oxytocin , PMA and EGF stimulation of PGE2 production.
Prostaglandins, leukotrienes, and essential fatty acids  •  1993  |  View Paper
Although ovarian steroids showed no effect on OT receptors, forskolin (an adenylate cyclase activator) and dibutyryl cAMP caused 1.5- to 1.6-fold increases in specific binding of OT without changing the binding affinity.
Biology of reproduction  •  1997  |  View Paper
(Bu)2AMP, forskolin , or cholera toxin caused 2- to 8-fold increases in specific binding of iodinated OT antagonist.
Endocrinology  •  1993  |  View Paper
Judging from the greater effects on PGE2 release, these results suggest that forskolin and cortisol up-regulate the signal response mechanism to OT as well as the OTR concentration.
Endocrinology  •  1993  |  View Paper
Both forskolin and PMA (phorbol 12-myristate 13-acetate) increased CRF, AVP and oxytocin release, while dexamethasone and aldosterone only reduced basal secretion of CRF.
The Journal of endocrinology  •  1992  |  View Paper
Forskolin elicited a 3-fold greater increase in cyclic AMP in the neural lobe than in the supraoptic nucleus and enhanced the sensitivity of the tissues to both vasopressin and oxytocin.
Neuroscience Letters  •  1990  |  View Paper
(Bu)2cAMP and forskolin also inhibited the effect of oxytocin on intracellular calcium.
Endocrinology  •  1989  |  View Paper
Show More