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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Oxytetracycline
supplement:
Vitamin C
Research Papers that Mention the Interaction
“ Ascorbic acid contained in the injection preparation of oxytetracycline interfered with the inhibitory effect of this antibiotic on the TTC reduction by staphylococci and actually increased the activity of reduction.”
On the mechanism of action of tetracycline antibiotics“ Oxytetracycline also caused a significant reduction in the activities of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione (GSH), vitamin C and vitamin E in liver.”
Influence of naringenin on oxytetracycline mediated oxidative damage in rat liver.“Conclusion: The present study revealed the preventive role of NSO and/or AA against the toxic effects of OTC through their free radical-scavenging and potent antioxidant activities.”
Effects of Nigella sativa oil and ascorbic acid against oxytetracycline-induced hepato-renal toxicity in rabbits“The formation of carcinogenic N-nitroso compounds by the chemical reaction between nitrous acid and oxytetracycline , morpholine, piperazine, N-methylaniline, methylurea, and (in some experiments) dimethylamine was blocked by ascorbic acid.”
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