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Last Updated: 3 months ago

Possible Interaction: Oxyquinoline and Ferrous

supplement:

Ferrous

Research Papers that Mention the Interaction

Follow-up studies were carried out on one of the series identified, 8-hydroxyquinolines , which were shown by crystallographic analyses to inhibit by binding to the active site Fe(II ) and to modulate demethylation at the H3K9 locus in a cell-based assay.
PloS one  •  2010  |  View Paper
Of the quinoline compounds tested, xanthurenic acid and 8-quinolinol with 8-hydroxyl group stimulated the autooxidation of ferrous ion , but kynurenic acid and quinaldic acid did not affect the oxidation of ferrous ion.
Biometals  •  2005  |  View Paper
IT has been shown that the antibacterial action of 8-hydroxyquinoline is due to its ability to combine with ferrous , ferric and cupric ions accidentally present in the medium, the complexes thus formed being the true toxic agents1.
Nature  •  1953  |  View Paper