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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Oxyquinoline
supplement:
Ferrous
Research Papers that Mention the Interaction
“Follow-up studies were carried out on one of the series identified, 8-hydroxyquinolines , which were shown by crystallographic analyses to inhibit by binding to the active site Fe(II ) and to modulate demethylation at the H3K9 locus in a cell-based assay.”
Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors“ Ferrous iron was able to negate the inhibition achieved by alpha, alpha'-bipyridyl, and 8-hydroxyquinoline.”
The effect of metal chelators and other metabolic inhibitors on the growth of Bifidobacterium bifidus var. Pennsylvanicus.“IT has been shown that the antibacterial action of 8-hydroxyquinoline is due to its ability to combine with ferrous , ferric and cupric ions accidentally present in the medium, the complexes thus formed being the true toxic agents1.”
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