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“As expected, loading the cells with Fe(II)/Fe(III ) using 8-hydroxyquinoline as a carrier had an adverse effect on their viability as did treatment with a neurotoxin, 6-hydroxydopamine, that releases iron from ferritin storage.”
The Journal of pharmacology and experimental therapeutics • 2000 | View Paper
“IT has been shown that the antibacterial action of 8-hydroxyquinoline is due to its ability to combine with ferrous, ferric and cupric ions accidentally present in the medium, the complexes thus formed being the true toxic agents1.”