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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Following restraint stress-induced reinstatement of oxycodone CPP, OT significantly increased mRNA levels of Dnmt1, decreased Tet1 mRNA, synaptic proteins and synaptic density in the hippocampus.”
“ OT markedly inhibited global 5-mC changes induced by oxycodone CPP in the four phases.”
“Our results suggested that OT could be specific manipulation on oxycodone addiction.”
“Our study indicated that reversal of global DNA hypomethylation through OT could significantly attenuate the rewarding effects induced by oxycodone.”
Reversal of oxycodone conditioned place preference by oxytocin: Promoting global DNA methylation in the hippocampus“Intracerebroventricular (ICV) administration of oxytocin (2.5 μg/μl) specifically blocked oxycodone relapse , possibly by inhibition of Arc, Dlg1, Dlg4, and Syn1 hypomethylation in oxycodone-treated rats.”
“Intracerebroventricular (ICV) administration of oxytocin (2.5 μg/μl) specifically blocked oxycodone relapse , possibly by inhibition of Arc, Dlg1, Dlg4, and Syn1 hypomethylation in oxycodone‐treated rats.”
Oxytocin prevents cue‐induced reinstatement of oxycodone seeking: Involvement of DNA methylation in the hippocampus
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