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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Oxatomide and Calcium Supplement

Research Papers that Mention the Interaction

Oxatomide caused a concentration related inhibition of calcium ionophore-induced histamine release with the IC50 value of 5 x 10(-5) mol/l.
Arzneimittel-Forschung  •  1995  |  View Paper
In mast cells, oxatomide inhibits the increase of cytosolic calcium elicited during mast cell activation.
Annales de dermatologie et de venereologie  •  1990  |  View Paper
Furthermore, oxatomide inhibits 45Ca2+ uptake by guinea pig ileum after acetylcholine stimulation which constitutes strong evidence that inhibition of calcium ion utilization by smooth muscle cells plays a major role in the mode of action of oxatomide.
Allergologia et immunopathologia  •  1986  |  View Paper
Oxatomide at a concentration of 10 microM showed a significant inhibition on the histamine release induced by the calcium ionophore A-23187.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  1982  |  View Paper