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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Oxaliplatin
supplement:
Diindolylmethane
Research Papers that Mention the Interaction
“ DIM pretreatment of pancreatic cancer cells led to a significantly increased apoptosis (P < 0.01) with suboptimal concentrations of chemotherapeutic agents (cisplatin, gemcitabine, and oxaliplatin ) compared with monotherapy.”
“Most importantly, using an orthotopic animal model, we found reduction in tumor size (P < 0.001) when DIM was given in combination with oxaliplatin compared with monotherapy.”
3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer.
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