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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Oxacillin and Polyphenols

supplement:

Polyphenols

Research Papers that Mention the Interaction

The MICs of oxacillin for each of the 13 MRSA strains were reduced between 8- and 128-fold when these strains were coincubated with sub-MIC (≤0.5× MIC) levels of TPP , demonstrating that the combination of TPP plus oxacillin was synergistic for all of the clinical MRSA isolates.
These studies demonstrate that TPP can differentially stimulate the expression of various proteins in these bacteria and synergize the bactericidal activity of oxacillin for MRSA.
Current Microbiology  •  2008  |  View Paper
Minimum inhibitory concentration (MIC) values for oxacillin were reduced from 256 and 512 to 1-4 mg/l, respectively, in the presence of these polyphenols.
International journal of antimicrobial agents  •  2004  |  View Paper