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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ovalbumin
drug:
Zafirlukast
Research Papers that Mention the Interaction
“The antihistamines mepyramine (1 μM) … μM), the leukotriene antagonist zafirlukast (0.1 μM), or the cyclooxygenase enzyme (COX) inhibitor diclofenac (10 … a parallel and rightward shift in the dose-response relation for OVA , providing evidence for contributions of histamine, cysteinyl-leukotrienes, … to the OVA-induced bronchoconstriction in the IPL.”
Interactions among Three Classes of Mediators Explain Antigen-Induced Bronchoconstriction in the Isolated Perfused and Ventilated Guinea Pig Lung“Similarly, the combination of mepyramine, diclofenac and zafirlukast significantly attenuated the lung responses to adenosine and ovalbumen.”
“When two antagonists were combined, only mepyramine and zafirlukast significantly reduced the lung responses to adenosine and ovalbumen.”
“Pranlukast or zafirlukast (5 μM each) significantly suppressed ovalbumin‐induced secretion in tracheae from sensitized guinea‐pigs by 70% and 65%, respectively.”
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