Possible Interaction: Ovalbumin and Progesterone

“Administration of progesterone induced the expression of ovalbumin mRNA in the surface epithelial cells.”

“The concentrations of the specific proteins ovalbumin and avidin in quail oviduct increase during estrogen and progesterone treatment of immature animals.”

“Estrogen and progesterone markedly stimulate transcription of ovalbumin and conalbumin (transferrin) genes in chick oviduct as measured by hybridization of labeled RNA synthesized in isolated nuclei to immobilized plasmid DNA containing these gene sequences.”

“In contrast, progesterone administration results in a preferential shift of ovalbumin mRNA relative to total RNA, suggesting a preferential effect of progesterone on initiation of protein synthesis with ovalbumin mRNA.”

“expression of the ovalbumin gene is modulated by estrogen and progesterone , so that its structure may be compared in both active and inactive states.”

“With progesteone , there is a lag of about 2 hr before either ovalbumin or conalbumin mRNA begins to accumulate.”

“Levels of messenger RNA coding for ovalbumin , as detected by hybridization with labeled complementary DNA, increase in oviducts of withdrawn chicks within 2--3 of the injection of estrogen, progesterone or estrogen + progesterone.”

“ Progesterone causes a more rapid increase in both ovalbumin mRNA sequences and ovalbumin synthesis with a lag period of only 90 min.”

“We also found that OVA tended to raise maternal inflammatory and OS biomarker levels as well as to cause inappropriate levels of pregnancy hormones progesterone (P4) and estrogen (E2) although insignificant.”

“Of several blocking agents tested bovine serum albumin was superior in performance, whereas the combination of ovalbumin and progesterone substantially influenced test results.”