“The lung tissue released not only histamine but also cytotoxic … L929 cells 2 and 4 h after incubation with dinitrophenyl … ovalbumin (DNP-OVA) following passive sensitization with anti-DNP monoclonal rat IgE antibody, whereas neither …-OVA nor anti-DNP IgE antibody could induce the cytotoxic activity when used solely.”