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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Orotic Acid
drug:
Uracil
Research Papers that Mention the Interaction
“In normal, unoperated rats, administration of 100 mg/kg OA significantly increased hepatic uracil and cytosine nucleotide concentrations, then increased plasma uridine (+124%) and cytidine (+55%), and transiently increased myocardial uracil nucleotides (+21%).”
Cardioprotection by orotic acid: metabolism and mechanism of action.“When orotic acid was combined with uracil , the uracil-induced hypercholesteremia and atherogenesis were significantly inhibited, particularly in the females.”
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