Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Orotic Acid and Uracil

supplement:

Orotic Acid

drug:

Uracil

Research Papers that Mention the Interaction

In normal, unoperated rats, administration of 100 mg/kg OA significantly increased hepatic uracil and cytosine nucleotide concentrations, then increased plasma uridine (+124%) and cytidine (+55%), and transiently increased myocardial uracil nucleotides (+21%).
Journal of molecular and cellular cardiology  •  1997  |  View Paper
When orotic acid was combined with uracil , the uracil-induced hypercholesteremia and atherogenesis were significantly inhibited, particularly in the females.
Circulation research  •  1960  |  View Paper