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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Orotic Acid and Thioguanine

supplement:

Orotic Acid

Research Papers that Mention the Interaction

6-Thioguanine induced a marked depression in the rate of incorporation of thymidine- 3 H and orotic acid-6- 14 C into DNA and RNA, respectively.
Cancer research  •  1965  |  View Paper
Uracil incorporation into RNA pyrimidines was more specifically depressed than was RNA synthesis, whereas the conversion of orotic acid into RNA pyrimidines was enhanced during growth with thioguanine.
Biochemical pharmacology  •  1965  |  View Paper