Possible Interaction: Ornithine and Proline

“ Proline prevented the cytotoxicity of ornithine.”

“The resultant greater hepatic ornithine concentrations may represent a mechanism to facilitate tissue repair, by favoring the production of polyamines and/or proline.”

“ Proline prevented the inhibition of [(3)H]thymidine incorporation by ornithine in 5-FMOrn-treated epithelioid cells.”

“These results suggest that the upstream region of argB on the arg operon … an important role in interacting with ArgR under proline-supplemented conditions and that proline causes an increase in the endogenous level of ornithine by reducing the binding affinity of ArgR to the upstream region of argB.”

“Increases in concentration occurred when proline, ornithine , and glutamate were present in solution, with proline increasing the concentration by more than 3-fold compared to that of the control.”

“We have measured the rate of proline formation from ornithine in the presence of physiologic concentrations of proline.”

“The primary products from ornithine fermented in the presence of proline were acetate, ammonia, alanine, and CO(2), in order of concentration.”

“When an equimolar amount of proline was added along with ornithine , very little delta-aminovalerate was produced from the ornithine, but essentially all of the proline was reduced to this compound.”

“When an equimolar amount of proline was added along with ornithine , very little δ-aminovalerate was produced from the ornithine, but essentially all of the proline was reduced to this compound.”