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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ornithine
supplement:
Orotic Acid
Research Papers that Mention the Interaction
“Increased orotic acid production is reduced or prevented by inclusion of the urea cycle intermediates arginine, citrulline or ornithine.”
Metabolic aberrations associated with arginine deficiency.“To prevent the hyperammonemic and orotic aciduric responses with ornithine , its plasma concentrations needed to be higher than normal.”
“Administration of ornithine together with glycine completely suppressed the synthesis of orotic acid , but promoted a twofold increase of urea excretion.”
Cycloheximide sensitivity of orotic acid biosynthesis induced by ammonia and glycine administration.
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