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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Ondansetron
supplement:
Yohimbine
Research Papers that Mention the Interaction
“ Ondansetron was unable to rescue the reduction in duration of anesthesia induced by either rolipram or yohimbine.”
Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats“The stimulatory effect of ondansetron (10(-6) M) on electrically evoked contractions was antagonized by yohimbine , a 5-HT2B receptor antagonist, but not by SDZ 205-557 (2-methoxy-4-amino-5-chloro-benzoic acid 2-[diethylamino] ethyl ester), a 5-HT4 receptor antagonist.”
“This stimulatory effect of ondansetron on acetylcholine-induced contractions was antagonized by yohimbine.”
“The antinociceptive activity was inhibited by the pretreatment with ondansetron and yohimbine , indicating that the serotoninergic and adrenergic systems could participate in the mechanism underlying the analgesic activity of vanillic acid.”
Pharmacological mechanism underlying the antinociceptive activity of vanillic acid
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