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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Omeprazole
supplement:
Tryptophan
Research Papers that Mention the Interaction
“We conclude … or TRP … omeprazole treatment, significantly accelerates healing rate of H. pylori infected chronic gastroduodenal ulcers over that obtained with omeprazole alone and this likely depends … significant rise in plasma MT and possibly also in leptin levels, both hormones involved in the mechanism of gastroprotection and ulcer healing.”
Effects of melatonin and tryptophan on healing of gastric and duodenal ulcers with Helicobacter pylori infection in humans.“After treatment with omeprazole plus melatonin (group B) or Trp (group C), plasma melatonin levels rose several‐fold above initial values.”
“Plasma gastrin level also rose significantly during treatment with omeprazole plus melatonin or Trp , but it was also significantly increased in patients treated with omeprazole plus placebo.”
“We conclude that melatonin or Trp , when added to omeprazole treatment, accelerates ulcer healing and this likely depends mainly upon the significant increments in plasma melatonin.”
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