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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Omeprazole and St John's Wort

supplement:

St John's Wort

Research Papers that Mention the Interaction

Clinical trials indicate …’s wort Hypericum perforatum ), via cytochrome P450 (CYP) and/or P-glycoprotein induction, reduces the plasma concentrations (and/or increases the …, amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoquine, digoxin, erythromycin, fexofenadine, gliclazide, imatinib, indinavir, irinotecan, ivabradine, mephenytoin, methadone, midazolam, nifedipine, omeprazole , oral contraceptives, quazepam, simvastatin, …, voriconazole and warfarin.
Drugs  •  2012  |  View Paper
Meanwhile, low efficacy of omeprazole treatment would be anticipated, as omeprazole elimination could be significantly induced by comedicated efavirenz and herb medicines such as St John’s wort , Ginkgo biloba, and yin zhi huang.
Therapeutics and clinical risk management  •  2013  |  View Paper