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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Omeprazole
supplement:
St John's Wort
Research Papers that Mention the Interaction
“Clinical trials indicate …’s wort Hypericum perforatum ), via cytochrome P450 (CYP) and/or P-glycoprotein induction, reduces the plasma concentrations (and/or increases the …, amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoquine, digoxin, erythromycin, fexofenadine, gliclazide, imatinib, indinavir, irinotecan, ivabradine, mephenytoin, methadone, midazolam, nifedipine, omeprazole , oral contraceptives, quazepam, simvastatin, …, voriconazole and warfarin.”
Interactions Between Herbal Medicines and Prescribed Drugs“Meanwhile, low efficacy of omeprazole treatment would be anticipated, as omeprazole elimination could be significantly induced by comedicated efavirenz and herb medicines such as St John’s wort , Ginkgo biloba, and yin zhi huang.”
Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management
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