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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Omeprazole
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“Although the administration of omeprazole suspension buffered by NaHCO3 solution did not produce a significant increase … area under the concentration-time curve (AUC) value compared with non-buffered group, the administration of NaHCO3 buffer immediately after … of omeprazole suspension buffered by NaHCO3 caused a … increase in the AUC value.”
“These results suggest that the NaHCO3 treatment following the administration of omeprazole buffered suspension effectively decreased the degradation of the compound by gastric acid.”
Pharmacokinetic evaluation of omeprazole suspension following oral administration in rats: effect of neutralization of gastric acid.
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