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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Omeprazole and Secretin

supplement:

Secretin

Research Papers that Mention the Interaction

Mean plasma secretin in the omeprazole group was significantly lower in phases I and III (p less than 0.05).
The immediate postprandial mean value of secretin was significantly lower in the omeprazole group (p less than 0.05).
We conclude that 40 mg omeprazole elicits i) a phase-related increase in fasting plasma gastrin, ii) a decrease in secretin in phases I and III, iii) an augmented meal-stimulated gastrin response, and iv) a secretin response characterized by a significantly lower mean in the immediate postprandial period.
Scandinavian journal of gastroenterology  •  1992  |  View Paper
The results suggest that exposure of acid‐secreting gastric mucosa to omeprazole widens the interepithelial spacing in a manner that may facilitate enhanced macromolecular transport.
The Journal of pharmacy and pharmacology  •  2002  |  View Paper