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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Omeprazole
supplement:
Quinine
Research Papers that Mention the Interaction
“There was a significant correlation between the MR of quinine and omeprazole sulphone formation (r=0.52, P<0.01), but not to the MRs of the other probes.”
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man“When the plasma/serum concentrations possibly attained after their usual therapeutic doses were taken into account, tetracycline, doxycycline, omeprazole , ketoconazole, nifedipine, troleandomycin and erythromycin are likely to be inhibitors of quinine metabolism in patients when these drugs are co-administrated with quinine.”
“ Omeprazole and quinine combinations were synergistic; however, chloroquine and omeprazole combinations were antagonistic.”
Synergistic In Vitro Antimalarial Activity of Omeprazole and Quinine
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