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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Vitamin C
Research Papers that Mention the Interaction
“ Vitamin C increased the response to bradykinin and restored the inhibiting effect of L-NMMA while preventing the effect of ouabain.”
Calcium Antagonist Treatment by Lercanidipine Prevents Hyperpolarization in Essential Hypertension“In this subgroup, vitamin C increased the vasodilation to acetylcholine and restored the inhibiting effect of L-NMMA.”
“Only in older sedentary individuals, Vitamin C increased response to acetylcholine (p<0.001) and restored the inhibiting effect of L-NMMA (p<0.01).”
“ Vitamin C , which decreased plasma isoprostanes and increased plasma antioxidant capacity, increased the response to ACh and restored the inhibiting effect of L-NMMA.”
“A combination of MEL + NMMA completely blocked both AA and LHRH release, supporting a role for NO in the releasing action.”
Inhibition of Melatonin-lnduced Ascorbic Acid and LHRH Release by a Nitric Oxide Synthase and Cyclic GMP Inhibitor“Membrane depolarization caused by incubation in high potassium (K+ = 28 or 56 mM) medium stimulated release of FSH, LH, and AA that was blocked by NMMA.”
“ NMMA also inhibited LHRH-induced LH and FSH release and gonadotropin release in the presence of both LHRH and AA , whereas sodium nitroprusside, a releaser of NO, stimulated LH and FSH release.”
“The FSH and LH release in response to AA was blocked by incubation with NG-monomethyl-l-arginine (NMMA) (300 μM), a competitive inhibitor of NO synthase.”
“An inhibitor of NO synthase (NOS), N(G)-monomethyl-l-arginine (NMMA), prevented the increase in medium concentrations of AA and LH-RH induced by high [K(+)], suggesting that NO mediates release of both AA and LH-RH.”
“ Vit C increased the response to ACh (509 ± 57%; P < 0.01 vs ACh alone) and restored the inhibiting effect of L-NMMA (332 ± 42, -34 ± 8%; P < 0.001).”
6D.02: GHRELIN RESTORES NITRIC OXIDE AVAILABILITY IN THE FOREARM MICROCIRCULATION OF ESSENTIAL HYPERTENSIVE PATIENTS
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