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“Microinjection of NG-monomethyl-L-arginine (L-NMMA), an inhibitor of the formation of NO, prevented cerebral vasoconstrictor responses induced by microinjection of l-glutamate into the NTS (n=10).”
“These effects of L-glutamate or NMDA were blocked by prior administration of NO synthase inhibitor N(G)-methyl-L-arginine or N(G)-nitro-L-arginine methyl ester.”
“Prior microinjection of NG-monomethyl-L-arginine (L-NMMA), an inhibitor of the formation of NO from L-arginine, into the NTS blocked the spinal cord vasoconstrictor response produced by microinjection of L-glutamate into the NTS (n = 10).”
“This effect of L-glutamate was reduced by prior intra NRM administration of NO synthase inhibitor NG-methyl-L-arginine or NG-nitro-L-arginine methyl ester (L-NAME, 0.1 µl, 100 nM).”