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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Oligosaccharides and Trimethoprim

Research Papers that Mention the Interaction

Prodrug strategies based on conjugation of oligosaccharides to trimethoprim have great potential for increasing the solubility of trimethoprim and lowering its toxicity, but they have been challenging to develop due to the sensitivity of trimethoprim to chemical modifications, and the rapid degradation of oligosaccharides in serum.
Bioconjugate chemistry  •  2018  |  View Paper