Possible Interaction: Oligosaccharides and Iron, Dietary

“ Nondigestible oligosaccharides have been shown to increase the absorption of several minerals (calcium, magnesium, in some cases phosphorus) and trace elements (mainly copper, iron , zinc).”

“In conclusion, HMO profile may modulate the infant gut microbiota response to fortificant iron ; compared to infants of secretor mothers, infants of non-secretor mothers may be more vulnerable to the adverse effect of iron but also benefit more from the co-provision of GOS.”

“Conclusion A MNP containing a low dose of highly bioavailable iron reduces anaemia, and the addition of GOS mitigates most of the adverse effects of iron on the gut microbiome and morbidity in African infants.”

“A recent report by the same group showed that the inclusion of GOSs in an iron-containing MNP can mitigate the adverse effects of iron on the gut microbiome in infants in Kenya (7).”

“It can be concluded that Galacto Oligosaccharides helped enhance the absorption of iron in anemic rats, reflected by increase in serum iron and serum ferritin levels and decrease in serum transferrin and total iron binding capacity.”