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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Oleic Acid and Tenoxicam


Oleic Acid

Research Papers that Mention the Interaction

The above results indicate that the combinations of lipophilic vehicles like OA , LOA or OAl and hydrophilic vehicles like PG can be used for enhancing the skin permeation of tenoxicam.
International journal of pharmaceutics  •  2002  |  View Paper
It was found that OA content markedly increased TEN absorption when compared to the control gel; the highest drug flux was obtained by 15% of OA.
Skin pretreatment with OA , independently of the vehicle used to dissolve the fatty acid, dramatically improved TEN percutaneous penetration.
The absorption rate of TEN increased in parallel with increasing OA concentration, due to the alteration of the stratum corneum caused by this enhancer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V  •  2001  |  View Paper