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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Oleic Acid
drug:
Somatostatin
Research Papers that Mention the Interaction
“In five normal persons infusion of 0, 5, 10, 20 and 40 mM oleic acid dose-dependently increased the levels of somatostatin during as well as after gallbladder emptying.”
Effects of oleic acid and endogenous bile on duodenal secretion of somatostatin in man“Treatment with either caprylic acid (5 x 10(-3) M) or oleic acid (5 x 10(-5) M) for 90 min inhibited basal somatostatin secretion in both hypothalamic and cortical cell cultures.”
Effects of free fatty acids on somatostatin secretion, content and mRNA levels in cortical and hypothalamic fetal rat neurones in monolayer culture.“ Somatostatin (100 nM) inhibited maximal oleic acid-stimulated NTLI release by 92%.”
“…,somatostatin 25-200 ng X min-1) reduced the basal p-NTLI levels, as well as … in p-NTLI levels induced by CaCl2 (10 and 25 mg X kg-1), fat ( oleic acid , 0.5 ml) and bombesin (25 and 125 … X kg-1), in a dose-related manner.”
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