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Last Updated: 24 days ago

Possible Interaction: Oleic Acid and Bosentan

supplement:

Oleic Acid

Research Papers that Mention the Interaction

ConclusionsPretreatment, but not treatment, with bosentan , in the dose used, blunted the oleic acid-induced increase in pulmonary vascular resistance, suggesting that endothelins contribute to the increase in pulmonary vascular tone in the early stages of oleic acid lung injury.
Intensive Care Medicine  •  2003  |  View Paper
Bosentan and Ro 46-8443 (at doses of 30 and 10 mg x kg(-1) respectively) inhibited the neutrophil infiltration induced by oleic acid by approx.
Bosentan , the antagonist of endothelin receptors (ET(A) and ET(B)) or the selective ET(B) receptor antagonists Ro 46-8443 or … 1 h before oleic acid at doses of 30, 10 and 30 mg x kg(-1) respectively) reduced the effect of oleic acid by 71%, … 79% respectively.
Clinical science  •  2002  |  View Paper