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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Ofloxacin and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

The genotoxic effect of ofloxacin was significantly decreased by standard antimutagens (sodium selenite, ascorbic acid , butylated hydroxyanisole and butylated hydroxytoluene) in the unicellular flagellate Euglena gracilis.
Mutation research  •  1996  |  View Paper
Out of 13 chemotherapeutical agents tested, ofloxacine , N-succinimidylofloxacine, fleroxacine, tetracycline, 6-thiatetracycline, and doxycycline reacted with ascorbic acid with the development of the superoxide radical (O2.-).
The kinetics of the process of the survival of cells within 24 hours demonstrated that a combination of ofloxacine as well as tetracycline with ascorbic acid produced a statistically significant increase in log10 of CFU/ml in S. aureus as well as E. coli.
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti  •  2000  |  View Paper