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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ofloxacin and Serine



Research Papers that Mention the Interaction

CONCLUSIONS To our knowledge, this is the first report that l- erine ca n potentiate the action of ofl oxacin or moxifloxacin against Gram-negative bacteria and could constitute a new strategy for the eradication of bacterial infections.
The underlying mechanism of this strategy is that the combination of serine with ofloxacin or moxifloxacin increases the NAD(+)/NADH ratio, disrupts the Fe-S clusters and increases the production of endogenous reactive oxygen species.
The Journal of antimicrobial chemotherapy  •  2016  |  View Paper