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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ofloxacin
supplement:
Ferrous Sulfate
Research Papers that Mention the Interaction
“Concomitant ingestion of ferrous sulphate reduced the AUC and peak plasma concentration of ofloxacin by 25% (P < 0.01) and 36% (P < 0.01), respectively.”
“It would also be advisable not to take ofloxacin with ferrous sulphate , especially if the organism causing infection is only moderately susceptible.”
The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.“In-vitro studies using simulated gastric fluid showed that ferrous sulphate , aluminium hydroxide and calcium carbonate reduced ofloxacin availability to 67.4%, 69.3% and 73.8%, respectively.”
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