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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Octanoic Acid
drug:
Ghrelin
Research Papers that Mention the Interaction
“Both dietary caprylic acid availability and GOAT activity may indeed be important to modulate octanoylated ghrelin concentration and functions.”
Dietary caprylic acid and ghrelin O-acyltransferase activity to modulate octanoylated ghrelin functions: What is new in this nutritional field?“Addition of octanoic acid or α-linolenic acid to MGN3-1 cells increased and decreased octanoyl ghrelin levels, respectively.”
“Ghrelin contains an octanoic acid at the third residue serine, and the presence of octanoic acid on ghrelin is critical to its physiological functions.”
“The Ser(3) residue of ghrelin is mainly modified by a n-octanoic acid.”
“The Ser(3) residue of ghrelin is modified by n-octanoic acid , a modification necessary for hormonal activity.”
“Moreover, synthetic ghrelin derivatives demonstrated that octanoic acid is not the only modification of the Ser(3) side chain to sustain the activity of ghrelin ; other acyl acid modifications maintained activity.”
Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides.
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