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Discover Supplement-Drug Interactions

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Possible Interaction: Nortriptyline and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

Yohimbine potentiated the effect of nortriptyline or amitriptyline administered in a single dose and the effect of imipramine and amitriptyline given for 2 weeks.
Psychopharmacology  •  2004  |  View Paper
However, the beneficial effects of NT on sustained attention and premature responses were attenuated by pretreatment with either yohimbine or propranolol.
Psychopharmacology  •  2012  |  View Paper
The reduction of noradrenaline (NA) utilization in the brain evoked by a single dose of antidepressants and the increase of NA utilization induced by chronic treatment with imipramine or nortriptyline were prevented by yohimbine.
Yohimbine and phentolamine administered in doses regarded as blocking presynaptic alpha-adrenoreceptors counteracted locomotor sedation elicited in rats by antidepressant drugs (imipramine, nortriptyline and amitriptyline).
Polish journal of pharmacology and pharmacy  •  1980  |  View Paper