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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Norgestrel
supplement:
Progesterone
Research Papers that Mention the Interaction
“ Progesterone and norethisterone showed maximum competition for norgestrel binding sites while chlormadinone acetate, oestradiol, testosterone and corticosterone competed poorly.”
Binding of norgestrel to receptor proteins in the human endometrium and myometrium.“Thus administration of small doses of Norgestrel appeared to reduce the ability of the corpus luteum to produce progesterone and this may be one of the ways in which Norgesterel exerts an antifertility effect.”
“Results showed that norgestrel inhibited or suppressed luteinizing hormone and follicle-stiumulating hormone peaks and decreased progesterone in serum and pregnanediol in urine.”
“Overall, administration of progesterone and the combinations of estradiol with norgestrel and desogestrel were shown to significantly decrease the rate of orthodontic tooth movement when given for longer periods (>3 weeks).”
Does exogenous female sex hormone administration affect the rate of tooth movement and root resorption? A systematic review of animal studies
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