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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Norgestrel and Progesterone

supplement:

Progesterone

Research Papers that Mention the Interaction

Progesterone and norethisterone showed maximum competition for norgestrel binding sites while chlormadinone acetate, oestradiol, testosterone and corticosterone competed poorly.
Journal of steroid biochemistry  •  1977  |  View Paper
Thus administration of small doses of Norgestrel appeared to reduce the ability of the corpus luteum to produce progesterone and this may be one of the ways in which Norgesterel exerts an antifertility effect.
The Journal of obstetrics and gynaecology of the British Commonwealth  •  1972  |  View Paper
Results showed that norgestrel inhibited or suppressed luteinizing hormone and follicle-stiumulating hormone peaks and decreased progesterone in serum and pregnanediol in urine.
Fertility and sterility  •  1971  |  View Paper
Overall, administration of progesterone and the combinations of estradiol with norgestrel and desogestrel were shown to significantly decrease the rate of orthodontic tooth movement when given for longer periods (>3 weeks).
PloS one  •  2021  |  View Paper