Possible Interaction: Norfloxacin and Glabridin

“A synergistic interaction was observed between norfloxacin and glabridin when used in combination against multidrug-resistant clinical isolate SA 4627 of Staphylococcus aureus at much lower concentrations, indicating the suitability of glabridin in combination therapy.”

“In in vitro combination experiments, glabridin was found to reduce the MIC of different antibiotics such as norfloxacin , oxacillin, and vancomycin by up to 4-fold, while the MIC of glabridin itself was found to be reduced by up to 8-fold in the presence of antibiotics.”